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Towards low cost, multiplex clinical genotyping: 4-fluorescent Kompetitive Allele-Specific PCR and its application on pharmacogenetics

Single-nucleotide polymorphisms (SNPs) is associated with efficacy of specific drugs. Although there are several methods for SNP genotyping in clinical settings, alternative methods with lower cost, higher throughout and less complexity are still needed. In this study, we modified Kompetitive Allele...

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Detalles Bibliográficos
Autores principales: Suo, Wei, Shi, Xiujin, Xu, Sha, Li, Xiao, Lin, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075562/
https://www.ncbi.nlm.nih.gov/pubmed/32176732
http://dx.doi.org/10.1371/journal.pone.0230445