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JC Virus infected choroid plexus epithelial cells produce extracellular vesicles that infect glial cells independently of the virus attachment receptor

The human polyomavirus, JCPyV, is the causative agent of progressive multifocal leukoencephalopathy (PML) in immunosuppressed and immunomodulated patients. Initial infection with JCPyV is common and the virus establishes a long-term persistent infection in the urogenital system of 50–70% of the huma...

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Detalles Bibliográficos
Autores principales: O’Hara, Bethany A., Morris-Love, Jenna, Gee, Gretchen V., Haley, Sheila A., Atwood, Walter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075641/
https://www.ncbi.nlm.nih.gov/pubmed/32130281
http://dx.doi.org/10.1371/journal.ppat.1008371