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The ProTide Prodrug Technology: From the Concept to the Clinic: Miniperspective

[Image: see text] The ProTide technology is a prodrug approach developed for the efficient intracellular delivery of nucleoside analogue monophosphates and monophosphonates. In this approach, the hydroxyls of the monophosphate or monophosphonate groups are masked by an aromatic group and an amino ac...

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Detalles Bibliográficos
Autores principales: Mehellou, Youcef, Rattan, Hardeep S., Balzarini, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075648/
https://www.ncbi.nlm.nih.gov/pubmed/28792763
http://dx.doi.org/10.1021/acs.jmedchem.7b00734