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Antagonistic regulation by insulin-like peptide and activin ensures the elaboration of appropriate dendritic field sizes of amacrine neurons

Establishing appropriate sizes and shapes of dendritic arbors is critical for proper wiring of the central nervous system. Here we report that Insulin-like Peptide 2 (DILP2) locally activates transiently expressed insulin receptors in the central dendrites of Drosophila Dm8 amacrine neurons to posit...

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Detalles Bibliográficos
Autores principales: Luo, Jiangnan, Ting, Chun-Yuan, Li, Yan, McQueen, Philip, Lin, Tzu-Yang, Hsu, Chao-Ping, Lee, Chi-Hon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075694/
https://www.ncbi.nlm.nih.gov/pubmed/32175842
http://dx.doi.org/10.7554/eLife.50568