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Enzymes involved in folate metabolism and its implication for cancer treatment
BACKGROUND/OBJECTIVES: Folate plays a critical role in DNA synthesis and methylation. Intracellular folate homeostasis is maintained by the enzymes folylpolyglutamate synthase (FPGS) and γ-glutamyl hydrolase (GGH). FPGS adds glutamate residues to folate upon its entry into the cell through a process...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Korean Nutrition Society and the Korean Society of Community Nutrition
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075736/ https://www.ncbi.nlm.nih.gov/pubmed/32256983 http://dx.doi.org/10.4162/nrp.2020.14.2.95 |