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Enzymes involved in folate metabolism and its implication for cancer treatment

BACKGROUND/OBJECTIVES: Folate plays a critical role in DNA synthesis and methylation. Intracellular folate homeostasis is maintained by the enzymes folylpolyglutamate synthase (FPGS) and γ-glutamyl hydrolase (GGH). FPGS adds glutamate residues to folate upon its entry into the cell through a process...

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Detalles Bibliográficos
Autor principal:	Kim, Sung-Eun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Nutrition Society and the Korean Society of Community Nutrition 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075736/ https://www.ncbi.nlm.nih.gov/pubmed/32256983 http://dx.doi.org/10.4162/nrp.2020.14.2.95

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