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Preclinical evaluation of [(18)F]FB-A20FMDV2 as a selective marker for measuring α(V)β(6) integrin occupancy using positron emission tomography in rodent lung
PURPOSE: Integrin α(v)β(6) belongs to the RGD subset of the integrin family, and its expression levels are a prognostic and theranostic factor in some types of cancer and pulmonary fibrosis. This paper describes the GMP radiolabelling of the synthetic 20 amino acid peptide A20FMDV2 (NAVPNLRGDLQVLAQK...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075836/ https://www.ncbi.nlm.nih.gov/pubmed/31897589 http://dx.doi.org/10.1007/s00259-019-04653-5 |