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Preclinical evaluation of [(18)F]FB-A20FMDV2 as a selective marker for measuring α(V)β(6) integrin occupancy using positron emission tomography in rodent lung

PURPOSE: Integrin α(v)β(6) belongs to the RGD subset of the integrin family, and its expression levels are a prognostic and theranostic factor in some types of cancer and pulmonary fibrosis. This paper describes the GMP radiolabelling of the synthetic 20 amino acid peptide A20FMDV2 (NAVPNLRGDLQVLAQK...

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Detalles Bibliográficos
Autores principales:	Onega, Mayca, Parker, Christine A., Coello, Christopher, Rizzo, Gaia, Keat, Nicholas, Ramada-Magalhaes, Joaquim, Moz, Sara, Tang, Sac-Pham, Plisson, Christophe, Wells, Lisa, Ashworth, Sharon, Slack, Robert J., Vitulli, Giovanni, Wilson, Frederick J., Gunn, Roger, Lukey, Pauline T., Passchier, Jan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075836/ https://www.ncbi.nlm.nih.gov/pubmed/31897589 http://dx.doi.org/10.1007/s00259-019-04653-5

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