Clinical quantification of the integrin αvβ6 by [(18)F]FB-A20FMDV2 positron emission tomography in healthy and fibrotic human lung (PETAL Study)

PURPOSE: The RGD-integrin, αvβ6, plays a role in the pathogenesis of pulmonary fibrosis through activation of transforming growth factor beta (TGFβ). This study sought to quantify expression of αvβ6 in the lungs of healthy humans and subjects with pulmonary fibrosis using the αvβ6-selective [(18)F]F...

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Detalles Bibliográficos
Autores principales: Lukey, Pauline T., Coello, Christopher, Gunn, Roger, Parker, Christine, Wilson, Frederick J., Saleem, Azeem, Garman, Nadia, Costa, Maria, Kendrick, Stuart, Onega, Mayca, Kang’ombe, Arthur R., Listanco, Allan, Davies, James, Ramada-Magalhaes, Joaquim, Moz, Sara, Fahy, William A., Maher, Toby M., Jenkins, Gisli, Passchier, Jan, Marshall, Richard P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075837/
https://www.ncbi.nlm.nih.gov/pubmed/31814068
http://dx.doi.org/10.1007/s00259-019-04586-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075837/
https://www.ncbi.nlm.nih.gov/pubmed/31814068
http://dx.doi.org/10.1007/s00259-019-04586-z

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