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A survey of TIR domain sequence and structure divergence

Toll-interleukin-1R resistance (TIR) domains are ubiquitously present in all forms of cellular life. They are most commonly found in signaling proteins, as units responsible for signal-dependent formation of protein complexes that enable amplification and spatial propagation of the signal. A less co...

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Detalles Bibliográficos
Autores principales: Toshchakov, Vladimir Y., Neuwald, Andrew F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075850/
https://www.ncbi.nlm.nih.gov/pubmed/32002590
http://dx.doi.org/10.1007/s00251-020-01157-7