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Development of an experimental method of systematically estimating protein expression limits in HEK293 cells

Protein overexpression sometimes causes cellular defects, although the underlying mechanism is still unknown. A protein’s expression limit, which triggers cellular defects, is a useful indication of the underlying mechanism. In this study, we developed an experimental method of estimating the expres...

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Detalles Bibliográficos
Autores principales: Mori, Yoshihiro, Yoshida, Yuki, Satoh, Ayano, Moriya, Hisao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075890/
https://www.ncbi.nlm.nih.gov/pubmed/32179769
http://dx.doi.org/10.1038/s41598-020-61646-3