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PRDM3 attenuates pancreatitis and pancreatic tumorigenesis by regulating inflammatory response

Pancreatic ductal adenocarcinoma (PDAC) is associated with metaplastic changes in the pancreas but the transcriptional program underlying these changes is incompletely understood. The zinc finger transcription factor, PRDM3, is lowly expressed in normal pancreatic acini and its expression increases...

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Detalles Bibliográficos
Autores principales: Ye, Jie, Huang, Anpei, Wang, Haitao, Zhang, Anni M. Y., Huang, Xiaojun, Lan, Qingping, Sato, Tomohiko, Goyama, Susumu, Kurokawa, Mineo, Deng, Chuxia, Sander, Maike, Schaeffer, David F., Li, Wen, Kopp, Janel L., Xie, Ruiyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075911/
https://www.ncbi.nlm.nih.gov/pubmed/32179733
http://dx.doi.org/10.1038/s41419-020-2371-x