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Long-term hippocampal interneuronopathy drives sex-dimorphic spatial memory impairment induced by prenatal THC exposure

Prenatal exposure to Δ(9)-tetrahydrocannabinol (THC), the most prominent active constituent of cannabis, alters neurodevelopmental plasticity with a long-term functional impact on adult offspring. Specifically, THC affects the development of pyramidal neurons and GABAergic interneurons via cannabino...

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Detalles Bibliográficos
Autores principales: de Salas-Quiroga, Adán, García-Rincón, Daniel, Gómez-Domínguez, Daniel, Valero, Manuel, Simón-Sánchez, Samuel, Paraíso-Luna, Juan, Aguareles, José, Pujadas, Mitona, Muguruza, Carolina, Callado, Luis F., Lutz, Beat, Guzmán, Manuel, de la Prida, Liset Menéndez, Galve-Roperh, Ismael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075920/
https://www.ncbi.nlm.nih.gov/pubmed/31982904
http://dx.doi.org/10.1038/s41386-020-0621-3