Transcriptome signature analysis repurposes trifluoperazine for the treatment of fragile X syndrome in mouse model

Fragile X syndrome (FXS) is a prevailing genetic disorder of intellectual disability and autism. There is no efficacious medication for FXS. Through in silico screening with a public database, computational analysis of transcriptome profile in FXS mouse neurons predicts therapeutic value of an FDA-a...

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Detalles Bibliográficos
Autores principales: Ding, Qi, Sethna, Ferzin, Wu, Xue-Ting, Miao, Zhuang, Chen, Ping, Zhang, Yueqi, Xiao, Hua, Feng, Wei, Feng, Yue, Li, Xuan, Wang, Hongbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075969/
https://www.ncbi.nlm.nih.gov/pubmed/32179850
http://dx.doi.org/10.1038/s42003-020-0833-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075969/
https://www.ncbi.nlm.nih.gov/pubmed/32179850
http://dx.doi.org/10.1038/s42003-020-0833-4

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