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Repression of G1/S Transition by Transient Inhibition of miR-10404 Expression in Drosophila Primordial Germ Cells

Cell-cycle quiescence is a common feature of early germline development in many animal species. In Drosophila germline progenitors (pole cells), both G2/M and G1/S transitions are blocked. G2/M transition is repressed by maternal Nanos through suppression of Cyclin B production. However, the molecul...

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Detalles Bibliográficos
Autores principales: Morita, Shumpei, Ota, Ryoma, Hayashi, Makoto, Kobayashi, Satoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075979/
https://www.ncbi.nlm.nih.gov/pubmed/32179474
http://dx.doi.org/10.1016/j.isci.2020.100950