Cargando…

Carboranyl Derivatives of Rofecoxib with Cytostatic Activity against Human Melanoma and Colon Cancer Cells

Owing to the involvement of cyclooxygenase-2 (COX-2) in carcinogenesis, COX-2-selective inhibitors are increasingly studied for their potential cytotoxic properties. Moreover, the incorporation of carboranes in structures of established anti-inflammatory drugs can improve the potency and metabolic s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Buzharevski, Antonio, Paskaš, Svetlana, Sárosi, Menyhárt-Botond, Laube, Markus, Lönnecke, Peter, Neumann, Wilma, Murganić, Blagoje, Mijatović, Sanja, Maksimović-Ivanić, Danijelа, Pietzsch, Jens, Hey-Hawkins, Evamarie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076013/ https://www.ncbi.nlm.nih.gov/pubmed/32179835 http://dx.doi.org/10.1038/s41598-020-59059-3

Ejemplares similares

Carboranyl Analogues of Ketoprofen with Cytostatic Activity against Human Melanoma and Colon Cancer Cell Lines
por: Buzharevski, Antonio, et al.
Publicado: (2019)

Carboranyl Analogues of Mefenamic Acid and Their Biological Evaluation
por: Useini, Liridona, et al.
Publicado: (2022)

Carborane-Based Analog of Rev-5901 Attenuates Growth of Colon Carcinoma In Vivo
por: Paskaš, Svetlana, et al.
Publicado: (2022)

The More the Better—Investigation of Polymethoxylated N-Carboranyl Quinazolines as Novel Hybrid Breast Cancer Resistance Protein Inhibitors
por: Stockmann, Philipp, et al.
Publicado: (2023)

Quinoline‐Conjugated Ruthenacarboranes: Toward Hybrid Drugs with a Dual Mode of Action
por: Gozzi, Marta, et al.
Publicado: (2019)

Synthesis and In Vitro Biological Evaluation of p-Carborane-Based Di-tert-butylphenol Analogs
por: Braun, Sebastian, et al.
Publicado: (2023)

Borcalein: a Carborane‐Based Analogue of Baicalein with 12‐Lipoxygenase‐Independent Toxicity
por: Kuhnert, Robert, et al.
Publicado: (2021)

Metallodrugs against Breast Cancer: Combining the Tamoxifen Vector with Platinum(II) and Palladium(II) Complexes
por: Kazimir, Aleksandr, et al.
Publicado: (2023)

Correction: Kazimir et al. Metallodrugs against Breast Cancer: Combining the Tamoxifen Vector with Platinum(II) and Palladium(II) Complexes. Pharmaceutics 2023, 15, 682
por: Kazimir, Aleksandr, et al.
Publicado: (2023)

Carborane-Based ABCG2-Inhibitors Sensitize ABC-(Over)Expressing Cancer Cell Lines for Doxorubicin and Cisplatin
por: Paskas, Svetlana, et al.
Publicado: (2023)

Modular Synthetic Approach to Carboranyl‒Biomolecules Conjugates
por: Kellert, Martin, et al.
Publicado: (2021)

2,2′‐Bipyridine‐Modified Tamoxifen: A Versatile Vector for Molybdacarboranes
por: Schwarze, Benedikt, et al.
Publicado: (2019)

Ruthenacarborane and Quinoline: A Promising Combination for the Treatment of Brain Tumors
por: Drača, Dijana, et al.
Publicado: (2021)

Exploring the Reactivity of B‐Connected Carboranylphosphines in Frustrated Lewis Pair Chemistry: A New Frame for a Classic System
por: Schulz, Jan, et al.
Publicado: (2022)

Reductive Rearrangement of a 1‐Phospha‐2‐azanorbornene
por: Wonneberger, Peter, et al.
Publicado: (2021)

Modulation of γ-Secretase Activity by a Carborane-Based Flurbiprofen Analogue
por: Saretz, Stefan, et al.
Publicado: (2021)

Ruthenacarborane–Phenanthroline Derivatives as Potential Metallodrugs
por: Kellert, Martin, et al.
Publicado: (2020)

Silver(I) Complexes of Two Flexible Bis‐phospholane Ligands: Metallamacrocycles, Polymeric Chains, and Metallacryptands
por: Boar, Paul, et al.
Publicado: (2020)

Mesoporous Silica Nanoparticles Enhance the Anticancer Efficacy of Platinum(IV)-Phenolate Conjugates in Breast Cancer Cell Lines
por: Predarska, Ivana, et al.
Publicado: (2022)

Facile modification of phosphole-based aggregation-induced emission luminogens with sulfonyl isocyanates
por: König, Nils, et al.
Publicado: (2023)

[Disulfanediylbis(ferrocenylthiophosphinato)-κ(2) O,O]titanocene tetrahydrofuran trisolvate
por: Karakus, Mehmet, et al.
Publicado: (2012)

Synthesis and In Vitro Evaluation of a Set of 6-Deoxy-6-thio-carboranyl d-Glucoconjugates Shed Light on the Substrate Specificity of the GLUT1 Transporter
por: Matović, Jelena, et al.
Publicado: (2022)

On the Discovery, Biological Effects, and Use of Cisplatin and Metallocenes in Anticancer Chemotherapy
por: Gómez-Ruiz, Santiago, et al.
Publicado: (2012)

Enlargement of a Modular System—Synthesis and Characterization of an s-Triazine-Based Carboxylic Acid Ester Bearing a Galactopyranosyl Moiety and an Enormous Boron Load
por: Kellert, Martin, et al.
Publicado: (2019)

Synergistic effect of gefitinib and rofecoxib in mesothelioma cells
por: Stoppoloni, Daniela, et al.
Publicado: (2010)

Selective inhibition of prostacyclin synthase activity by rofecoxib
por: Griffoni, Cristiana, et al.
Publicado: (2007)

Catalytic Activity Towards Hydrogen Evolution Dependent of the Degree of Conjugation and Absorption of Six Organic Chromophores
por: Aleksovska, Angela, et al.
Publicado: (2020)

Metals in Medicine
por: Kaluđerović, Goran N., et al.
Publicado: (2012)

Silver(I) 2,2'-(1,2-Phenylenedisulfanediyl)diacetic Acid as a Molecular Building Block for a Silver(I)-Cadmium(II) Coordination Polymer
por: Grosu, Ioana Georgeta, et al.
Publicado: (2015)

Borinostats: solid-phase synthesis of carborane-capped histone deacetylase inhibitors with a tailor-made selectivity profile
por: Selg, Christoph, et al.
Publicado: (2021)

Triphenyltin(IV) Carboxylates with Exceptionally High Cytotoxicity against Different Breast Cancer Cell Lines
por: Predarska, Ivana, et al.
Publicado: (2023)

Ring-Opening Reaction of 1-Phospha-2-Azanorbornenes via P-N Bond Cleavage and Reversibility Studies
por: Ramazanova, Kyzgaldak, et al.
Publicado: (2023)

Synthesis and (11)C-Radiolabelling of 2-Carboranyl Benzothiazoles
por: Gona, Kiran B., et al.
Publicado: (2015)

Preparation of dendritic carboranyl glycoconjugates as potential anticancer therapeutics
por: Swain, Biswa Ranjan, et al.
Publicado: (2020)

Rofecoxib for dysmenorrhoea: meta-analysis using individual patient data
por: Edwards, Jayne E, et al.
Publicado: (2004)

The Double-Faced Role of Nitric Oxide and Reactive Oxygen Species in Solid Tumors
por: Mijatović, Sanja, et al.
Publicado: (2020)

Asymmetric 1,3-dipolar cycloaddition reaction of chiral 1-alkyl-1,2-diphospholes with diphenyldiazomethane
por: Ganushevich, Yulia, et al.
Publicado: (2020)

Melanoma Cell Reprogramming and Awakening of Antitumor Immunity as a Fingerprint of Hyper-Harmonized Hydroxylated Fullerene Water Complex (3HFWC) and Hyperpolarized Light Application In Vivo
por: Markelić, Milica, et al.
Publicado: (2023)

Synergistic Catalysis in Heterobimetallic Complexes for Homogeneous Carbon Dioxide Hydrogenation
por: Fickenscher, Zeno B. G., et al.
Publicado: (2023)

Synthesis of P-stereogenic 1-phosphanorbornane-derived phosphine–phosphite ligands and application in asymmetric catalysis
por: Ramazanova, Kyzgaldak, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_tmt0kai65cr6k6is3kt3hqei43