Downregulation of Lysosomal Acid Ceramidase Mediates HMGB1-Induced Migration and Proliferation of Mouse Coronary Arterial Myocytes

High-mobility group box 1 protein (HMGB1) has been reported to trigger lysosome destabilization causing a wide of inflammatory diseases. The present study tested whether a lysosomal enzyme, acid ceramidase (AC), plays a critical role in HMGB1-induced alteration in ceramide metabolism and whether suc...

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Detalles Bibliográficos
Autores principales: Yuan, Xinxu, Bhat, Owais M., Lohner, Hannah, Zhang, Yang, Li, Pin-Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076051/
https://www.ncbi.nlm.nih.gov/pubmed/32211403
http://dx.doi.org/10.3389/fcell.2020.00111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076051/
https://www.ncbi.nlm.nih.gov/pubmed/32211403
http://dx.doi.org/10.3389/fcell.2020.00111

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