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Histone Lysine Demethylases KDM5B and KDM5C Modulate Genome Activation and Stability in Porcine Embryos

The lysine demethylases KDM5B and KDM5C are highly, but transiently, expressed in porcine embryos around the genome activation stage. Attenuation of KDM5B and KDM5C mRNA hampered embryo development to the blastocyst stage in fertilized, parthenogenetically activated and nuclear transfer embryos. Whi...

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Detalles Bibliográficos
Autores principales: Glanzner, Werner Giehl, Gutierrez, Karina, Rissi, Vitor Braga, de Macedo, Mariana Priotto, Lopez, Rosalba, Currin, Luke, Dicks, Naomi, Baldassarre, Hernan, Agellon, Luis B., Bordignon, Vilceu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076052/
https://www.ncbi.nlm.nih.gov/pubmed/32211412
http://dx.doi.org/10.3389/fcell.2020.00151