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Prostaglandin E Receptor 4 Antagonist in Cancer Immunotherapy: Mechanisms of Action
A highly expressed prostaglandin E(2) (PGE(2)) in tumor tissues suppresses antitumor immunity in the tumor microenvironment (TME) and causes tumor immune evasion leading to disease progression. In animal studies, selective inhibition of the prostaglandin E receptor 4 (EP4), one of four PGE(2) recept...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076081/ https://www.ncbi.nlm.nih.gov/pubmed/32210957 http://dx.doi.org/10.3389/fimmu.2020.00324 |