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Protein S-glutathionylation reactions as a global inhibitor of cell metabolism for the desensitization of hydrogen peroxide signals

The pathogenesis of many human diseases has been attributed to the over production of reactive oxygen species (ROS), particularly superoxide (O(2)(●-)) and hydrogen peroxide (H(2)O(2)), by-products of metabolism that are generated by the premature reaction of electrons with molecular oxygen (O(2)) b...

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Detalles Bibliográficos
Autor principal: Mailloux, Ryan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076094/
https://www.ncbi.nlm.nih.gov/pubmed/32171726
http://dx.doi.org/10.1016/j.redox.2020.101472