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Whole-cell fungal-mediated structural transformation of anabolic drug metenolone acetate into potent anti-inflammatory metabolites

Seven new derivatives, 6α-hydroxy-1-methyl-3-oxo-5α-androst-1-en-17-yl acetate (2), 6α,17β-dihydroxy-1-methyl-3-oxo-5α-androst-1-en (3), 7β-hydroxy-1-methyl-3-oxo-5α-androst-1-en-17-yl acetate (4), 15β,20-dihydroxy-1-methyl-3-oxo-5α-androst-1-en-17-yl acetate (5), 15β-hydroxy-1-methyl-3-oxo-5α-andro...

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Detalles Bibliográficos
Autores principales: Siddiqui, Mahwish, Atia-tul-Wahab, Jabeen, Almas, Wang, Yan, Wang, Wei, Atta-ur-Rahman, Choudhary, M. Iqbal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076145/
https://www.ncbi.nlm.nih.gov/pubmed/32195009
http://dx.doi.org/10.1016/j.jare.2020.02.009