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Glycoproteins C and D of PRV Strain HB1201 Contribute Individually to the Escape From Bartha-K61 Vaccine-Induced Immunity

The newly emerged pseudorabies virus (PRV) novel variants can escape from the immunity induced by the classical vaccine Bartha-K61. Here we investigated the underlying mechanisms by constructing chimeric mutants between epidemic strain HB1201 and the Bartha-K61 vaccine. Our analyses focused on three...

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Detalles Bibliográficos
Autores principales: Ren, Jianle, Wang, Haibao, Zhou, Lei, Ge, Xinna, Guo, Xin, Han, Jun, Yang, Hanchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076175/
https://www.ncbi.nlm.nih.gov/pubmed/32210933
http://dx.doi.org/10.3389/fmicb.2020.00323