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Inhibition of CXCR4 and CXCR7 Is Protective in Acute Peritoneal Inflammation

Our previous studies revealed a pivotal role of the chemokine stromal cell-derived factor (SDF)-1 and its receptors CXCR4 and CXCR7 on migratory behavior of polymorphonuclear granulocytes (PMNs) in pulmonary inflammation. Thereby, the SDF-1-CXCR4/CXCR7-axis was linked with adenosine signaling. Howev...

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Detalles Bibliográficos
Autores principales: Ngamsri, Kristian-Christos, Jans, Christoph, Putri, Rizki A., Schindler, Katharina, Gamper-Tsigaras, Jutta, Eggstein, Claudia, Köhler, David, Konrad, Franziska M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076176/
https://www.ncbi.nlm.nih.gov/pubmed/32210974
http://dx.doi.org/10.3389/fimmu.2020.00407