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In silico Docking Studies of Fingolimod and S1P(1) Agonists

The sphingosine-1-phosphate receptor 1 (S1P(1)), originally the endothelial differentiation gene 1 receptor (EDG-1), is one of five G protein–coupled receptors (GPCRs) S1P(1)(–)(5) that bind to and are activated by sphingosine-1-phosphate (S1P). The lipid S1P is an intermediate in sphingolipid homeo...

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Detalles Bibliográficos
Autores principales: Marciniak, Alexander, Camp, Sara M., Garcia, Joe G. N., Polt, Robin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076195/
https://www.ncbi.nlm.nih.gov/pubmed/32210822
http://dx.doi.org/10.3389/fphar.2020.00247