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Functional binding of E-selectin to its ligands is enhanced by structural features beyond its lectin domain

Selectins are key to mediating interactions involved in cellular adhesion and migration, underlying processes such as immune responses, metastasis, and transplantation. Selectins are composed of a lectin domain, an epidermal growth factor (EGF)-like domain, multiple short consensus repeats (SCRs), a...

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Detalles Bibliográficos
Autores principales: Aleisa, Fajr A., Sakashita, Kosuke, Lee, Jae Man, AbuSamra, Dina B., Al Alwan, Bader, Nozue, Shuho, Tehseen, Muhammad, Hamdan, Samir M., Habuchi, Satoshi, Kusakabe, Takahiro, Merzaban, Jasmeen S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076219/
https://www.ncbi.nlm.nih.gov/pubmed/31949047
http://dx.doi.org/10.1074/jbc.RA119.010910