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Large Volume Direct Injection Ultra-High Performance Liquid Chromatography–Tandem Mass Spectrometry-Based Comparative Pharmacokinetic Study between Single and Combinatory Uses of Carthamus tinctorius Extract and Notoginseng Total Saponins

The combination of Carthamus tinctorius extract (CTE) and notoginseng total saponins (NGTS), namely, CNP, presents a synergistic effect on myocardial ischemia protection. Herein, comparative pharmacokinetic studies between CNP and CTE/NGTS were conducted to clarify their synergistic mechanisms. A la...

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Detalles Bibliográficos
Autores principales: Chen, Jinfeng, Guo, Xiaoyu, Lu, Yingyuan, Shi, Mengling, Mu, Haidong, Qian, Yi, Wang, Jinlong, Lu, Mengqiu, Zhao, Mingbo, Tu, Pengfei, Song, Yuelin, Jiang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076352/
https://www.ncbi.nlm.nih.gov/pubmed/32093170
http://dx.doi.org/10.3390/pharmaceutics12020180