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Solubility, Antioxidation, and Oral Bioavailability Improvement of Mangiferin Microparticles Prepared Using the Supercritical Antisolvent Method

In view of the poor water solubility and low oral bioavailability of mangiferin (MG), in this study, the supercritical antisolvent (SAS) technology was used to prepare mangiferin microparticles (MG MPs) with N,N-dimethylformamide (DMF) as solvent and carbon dioxide as antisolvent, so as to improve i...

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Detalles Bibliográficos
Autores principales: Liu, Mengran, Liu, Yankun, Ge, Yunlong, Zhong, Zhaoliang, Wang, Zijian, Wu, Tong, Zhao, Xiuhua, Zu, Yuangang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076360/
https://www.ncbi.nlm.nih.gov/pubmed/31979138
http://dx.doi.org/10.3390/pharmaceutics12020090