Evaluation of the Solid Dispersion System Engineered from Mesoporous Silica and Polymers for the Poorly Water Soluble Drug Indomethacin: In Vitro and In Vivo

This work explored absorption efficacy via an in vivo imaging system and parallel artificial membrane penetration in indomethacin (IMC) solid dispersion (SD) systems. Two different polymer excipients—hydroxypropyl methylcellulose (HPMC) and Kollicoat IR as precipitation inhibitors (PIs)—combined wit...

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Detalles Bibliográficos
Autores principales: Xi, Ziyue, Zhang, Wei, Fei, Yali, Cui, Mingshu, Xie, Luyao, Chen, Lu, Xu, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076385/
https://www.ncbi.nlm.nih.gov/pubmed/32050600
http://dx.doi.org/10.3390/pharmaceutics12020144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076385/
https://www.ncbi.nlm.nih.gov/pubmed/32050600
http://dx.doi.org/10.3390/pharmaceutics12020144

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