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Biological Evaluation of Naproxen–Dehydrodipeptide Conjugates with Self-Hydrogelation Capacity as Dual LOX/COX Inhibitors

The use of peptide–drug conjugates is emerging as a powerful strategy for targeted drug delivery. Previously, we have found that peptides conjugated to a non-steroidal anti-inflammatory drug (NSAID), more specifically naproxen–dehydrodipeptide conjugates, readily form nanostructured fibrilar supramo...

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Detalles Bibliográficos
Autores principales: Moreira, Rute, Jervis, Peter J., Carvalho, André, Ferreira, Paula M. T., Martins, José A., Valentão, Patrícia, Andrade, Paula B., Pereira, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076388/
https://www.ncbi.nlm.nih.gov/pubmed/32028608
http://dx.doi.org/10.3390/pharmaceutics12020122