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Biological Evaluation of Naproxen–Dehydrodipeptide Conjugates with Self-Hydrogelation Capacity as Dual LOX/COX Inhibitors
The use of peptide–drug conjugates is emerging as a powerful strategy for targeted drug delivery. Previously, we have found that peptides conjugated to a non-steroidal anti-inflammatory drug (NSAID), more specifically naproxen–dehydrodipeptide conjugates, readily form nanostructured fibrilar supramo...
Autores principales: | Moreira, Rute, Jervis, Peter J., Carvalho, André, Ferreira, Paula M. T., Martins, José A., Valentão, Patrícia, Andrade, Paula B., Pereira, David M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076388/ https://www.ncbi.nlm.nih.gov/pubmed/32028608 http://dx.doi.org/10.3390/pharmaceutics12020122 |
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