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Species Differences in Stereoselective Pharmacokinetics of HSG4112, A New Anti-Obesity Agent

HSG4112, a racemic drug, is a new anti-obesity agent. In this study, the stereoselective pharmacokinetics of HSG4112 were investigated in rats and dogs, and the underlying mechanism was investigated. The plasma concentrations of HSG4112(S) and HSG4112(R) were quantitated in plasma from rats and beag...

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Detalles Bibliográficos
Autores principales: Bae, In Yong, Choi, Min Sun, Ji, Young Seok, Yoo, Sang-Ku, Kim, Kyungil, Yoo, Hye Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076457/
https://www.ncbi.nlm.nih.gov/pubmed/32028738
http://dx.doi.org/10.3390/pharmaceutics12020127