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Species Differences in Stereoselective Pharmacokinetics of HSG4112, A New Anti-Obesity Agent
HSG4112, a racemic drug, is a new anti-obesity agent. In this study, the stereoselective pharmacokinetics of HSG4112 were investigated in rats and dogs, and the underlying mechanism was investigated. The plasma concentrations of HSG4112(S) and HSG4112(R) were quantitated in plasma from rats and beag...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076457/ https://www.ncbi.nlm.nih.gov/pubmed/32028738 http://dx.doi.org/10.3390/pharmaceutics12020127 |