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Molecular Mechanisms of the Interactions of N-(2-Hydroxypropyl)methacrylamide Copolymers Designed for Cancer Therapy with Blood Plasma Proteins

The binding of plasma proteins to a drug carrier alters the circulation of nanoparticles (NPs) in the bloodstream, and, as a consequence, the anticancer efficiency of the entire nanoparticle drug delivery system. We investigate the possible interaction and the interaction mechanism of a polymeric dr...

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Detalles Bibliográficos
Autores principales:	Janisova, Larisa, Gruzinov, Andrey, Zaborova, Olga V., Velychkivska, Nadiia, Vaněk, Ondřej, Chytil, Petr, Etrych, Tomáš, Janoušková, Olga, Zhang, Xiaohan, Blanchet, Clement, Papadakis, Christine M., Svergun, Dmitri I., Filippov, Sergey K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076460/ https://www.ncbi.nlm.nih.gov/pubmed/32013056 http://dx.doi.org/10.3390/pharmaceutics12020106

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