Exploring the Complexity of Processing-Induced Dehydration during Hot Melt Extrusion Using In-Line Raman Spectroscopy

The specific aim in this study was to understand the effect of critical process parameters on the solid form composition of model drug compounds during hot melt extrusion using in-line Raman spectroscopy combined with Multivariate Curve Resolution-Alternating Least Squares (MCR-ALS) modeling for sem...

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Detalles Bibliográficos
Autores principales: Arnfast, Lærke, van Renterghem, Jeroen, Aho, Johanna, Bøtker, Johan, Raijada, Dhara, Baldursdóttir, Stefania, De Beer, Thomas, Rantanen, Jukka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076463/
https://www.ncbi.nlm.nih.gov/pubmed/32024085
http://dx.doi.org/10.3390/pharmaceutics12020116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076463/
https://www.ncbi.nlm.nih.gov/pubmed/32024085
http://dx.doi.org/10.3390/pharmaceutics12020116

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