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Preparation and Characterization of a Novel Swellable and Floating Gastroretentive Drug Delivery System (sfGRDDS) for Enhanced Oral Bioavailability of Nilotinib

Regarding compliance and minimization of side effects of nilotinib therapy, there is a medical need to have a gastroretentive drug delivery system (GRDDS) to enhance the oral bioavailability that is able to administer an optimal dose in a quaque die (QD) or daily manner. In this study, the influence...

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Detalles Bibliográficos
Autores principales: Lin, Hong-Liang, Chen, Ling-Chun, Cheng, Wen-Ting, Cheng, Wei-Jie, Ho, Hsiu-O, Sheu, Ming-Thau
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076507/
https://www.ncbi.nlm.nih.gov/pubmed/32041184
http://dx.doi.org/10.3390/pharmaceutics12020137