Impact of Mucin on Drug Diffusion: Development of a Straightforward In Vitro Method for the Determination of Drug Diffusivity in the Presence of Mucin

Mucosal drug delivery accounts for various administration routes (i.e., oral, vaginal, ocular, pulmonary, etc.) and offers a vast surface for the permeation of drugs. However, the mucus layer which shields and lubricates all mucosal tissues can compromise drugs from reaching the epithelial site, thu...

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Detalles Bibliográficos
Autores principales: Falavigna, Margherita, Stein, Paul C., Flaten, Gøril Eide, di Cagno, Massimiliano Pio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076515/
https://www.ncbi.nlm.nih.gov/pubmed/32079348
http://dx.doi.org/10.3390/pharmaceutics12020168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076515/
https://www.ncbi.nlm.nih.gov/pubmed/32079348
http://dx.doi.org/10.3390/pharmaceutics12020168

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