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Pharmacokinetics and Intestinal Metabolism of Compound K in Rats and Mice

We aimed to investigate the plasma concentration, tissue distribution, and elimination of compound K following the intravenous administration of compound K (2 mg/kg) in rats and mice. The plasma concentrations of compound K in mice were much higher (about five-fold) than those in rats. In both rats...

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Detalles Bibliográficos
Autores principales: Jeon, Ji-Hyeon, Kang, Bitna, Lee, Sowon, Jin, Sojeong, Choi, Min-Koo, Song, Im-Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076525/
https://www.ncbi.nlm.nih.gov/pubmed/32028741
http://dx.doi.org/10.3390/pharmaceutics12020129