Quantitative Proteomics of Clinically Relevant Drug-Metabolizing Enzymes and Drug Transporters and Their Intercorrelations in the Human Small Intestine

The levels of drug-metabolizing enzymes (DMEs) and transporter proteins in the human intestine are pertinent to determine oral drug bioavailability. Despite the paucity of reports on such measurements, it is well recognized that these values are essential for translating in vitro data on drug metabo...

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Detalles Bibliográficos
Autores principales: Couto, Narciso, Al-Majdoub, Zubida M., Gibson, Stephanie, Davies, Pamela J., Achour, Brahim, Harwood, Matthew D., Carlson, Gordon, Barber, Jill, Rostami-Hodjegan, Amin, Warhurst, Geoffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076527/
https://www.ncbi.nlm.nih.gov/pubmed/31959703
http://dx.doi.org/10.1124/dmd.119.089656

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076527/
https://www.ncbi.nlm.nih.gov/pubmed/31959703
http://dx.doi.org/10.1124/dmd.119.089656

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