Tablets of “Hydrochlorothiazide in Cyclodextrin in Nanoclay”: A New Nanohybrid System with Enhanced Dissolution Properties

Hydrochlorothiazide (HCT), a Biopharmaceutical Classification System (BCS) class IV drug, is characterized by low solubility and permeability, that negatively affect its oral bioavailability, reducing its therapeutic efficacy. The combined use of cyclodextrins (CDs) and nanoclays (NCs) recently prov...

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Detalles Bibliográficos
Autores principales: Maestrelli, Francesca, Cirri, Marzia, García-Villén, Fátima, Borrego-Sánchez, Ana, Viseras Iborra, César, Mura, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076548/
https://www.ncbi.nlm.nih.gov/pubmed/32013051
http://dx.doi.org/10.3390/pharmaceutics12020104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076548/
https://www.ncbi.nlm.nih.gov/pubmed/32013051
http://dx.doi.org/10.3390/pharmaceutics12020104

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