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Co-Encapsulation of Mitoxantrone and β-Elemene in Solid Lipid Nanoparticles to Overcome Multidrug Resistance in Leukemia

Multidrug resistance (MDR) due to P-glycoprotein (P-gp) overexpression is a major obstacle to successful leukemia chemotherapy. The combination of anticancer chemotherapy with a chemosensitizer of P-gp inhibitor is promising to overcome MDR, generate synergistic effects, and maximize the treatment e...

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Detalles Bibliográficos
Autores principales: Amerigos Daddy J.C., Kambere, Chen, Minglei, Raza, Faisal, Xiao, Yanyu, Su, Zhigui, Ping, Qineng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076650/
https://www.ncbi.nlm.nih.gov/pubmed/32102214
http://dx.doi.org/10.3390/pharmaceutics12020191