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Co-Encapsulation of Mitoxantrone and β-Elemene in Solid Lipid Nanoparticles to Overcome Multidrug Resistance in Leukemia
Multidrug resistance (MDR) due to P-glycoprotein (P-gp) overexpression is a major obstacle to successful leukemia chemotherapy. The combination of anticancer chemotherapy with a chemosensitizer of P-gp inhibitor is promising to overcome MDR, generate synergistic effects, and maximize the treatment e...
Autores principales: | Amerigos Daddy J.C., Kambere, Chen, Minglei, Raza, Faisal, Xiao, Yanyu, Su, Zhigui, Ping, Qineng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076650/ https://www.ncbi.nlm.nih.gov/pubmed/32102214 http://dx.doi.org/10.3390/pharmaceutics12020191 |
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