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Unforeseen Possibilities To Investigate the Regulation of Polyamine Metabolism Revealed by Novel C-Methylated Spermine Derivatives

[Image: see text] The biogenic polyamines, spermine (Spm) and spermidine, are organic polycations present in millimolar concentrations in all eukaryotic cells participating in the regulation of vital cellular functions including proliferation and differentiation. The design and biochemical evaluatio...

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Detalles Bibliográficos
Autores principales: Khomutov, Maxim, Hyvönen, Mervi T., Simonian, Alina, Formanovsky, Andrey A., Mikhura, Irina V., Chizhov, Alexander O., Kochetkov, Sergey N., Alhonen, Leena, Vepsäläinen, Jouko, Keinänen, Tuomo A., Khomutov, Alex R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076719/
https://www.ncbi.nlm.nih.gov/pubmed/31765147
http://dx.doi.org/10.1021/acs.jmedchem.9b01666