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P-Cresylsulfate, the Protein-Bound Uremic Toxin, Increased Endothelial Permeability Partly Mediated by Src-Induced Phosphorylation of VE-Cadherin

The goal of our study was to investigate the impact of p-cresylsulfate (PCS) on the barrier integrity in human umbilical vein endothelial cell (HUVEC) monolayers and the renal artery of chronic kidney disease (CKD) patients. We measured changes in the transendothelial electrical resistance (TEER) of...

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Detalles Bibliográficos
Autores principales: Chen, Shih-Chieh, Huang, Shin-Yin, Wu, Chia-Chun, Hsu, Chiung-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076797/
https://www.ncbi.nlm.nih.gov/pubmed/31973024
http://dx.doi.org/10.3390/toxins12020062