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Host–Receptor Post-Translational Modifications Refine Staphylococcal Leukocidin Cytotoxicity

Staphylococcal bi-component pore-forming toxins, also known as leukocidins, target and lyse human phagocytes in a receptor-dependent manner. S-components of the leukocidins Panton-Valentine leukocidin (PVL), γ-haemolysin AB (HlgAB) and CB (HlgCB), and leukocidin ED (LukED) specifically employ recept...

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Detalles Bibliográficos
Autores principales: Tromp, Angelino T., Van Gent, Michiel, Jansen, Joris P., Scheepmaker, Lisette M., Velthuizen, Anneroos, De Haas, Carla J.C., Van Kessel, Kok P.M., Bardoel, Bart W., Boettcher, Michael, McManus, Michael T., Van Strijp, Jos A.G., Lebbink, Robert Jan, Haas, Pieter-Jan A., Spaan, András N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076806/
https://www.ncbi.nlm.nih.gov/pubmed/32041354
http://dx.doi.org/10.3390/toxins12020106