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Host–Receptor Post-Translational Modifications Refine Staphylococcal Leukocidin Cytotoxicity
Staphylococcal bi-component pore-forming toxins, also known as leukocidins, target and lyse human phagocytes in a receptor-dependent manner. S-components of the leukocidins Panton-Valentine leukocidin (PVL), γ-haemolysin AB (HlgAB) and CB (HlgCB), and leukocidin ED (LukED) specifically employ recept...
Autores principales: | Tromp, Angelino T., Van Gent, Michiel, Jansen, Joris P., Scheepmaker, Lisette M., Velthuizen, Anneroos, De Haas, Carla J.C., Van Kessel, Kok P.M., Bardoel, Bart W., Boettcher, Michael, McManus, Michael T., Van Strijp, Jos A.G., Lebbink, Robert Jan, Haas, Pieter-Jan A., Spaan, András N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076806/ https://www.ncbi.nlm.nih.gov/pubmed/32041354 http://dx.doi.org/10.3390/toxins12020106 |
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