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Synthesis of crocetin derivatives and their potent inhibition in multiple tumor cells proliferation and inflammatory property of macrophage

BACKGROUND: Crocetin is a major active component of saffron, which has a wide range of pharmacological effects. However, due to its low solubility, the pharmacological effects of crocetin cannot be better utilized. METHODS: In this study, we modified the chemical structure of crocetin by conjugating...

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Detalles Bibliográficos
Autores principales: Wang, Mao-Ze, Gao, Jin, Chu, Yang, Niu, Jie, Chen, Ming, Shang, Qiang, Peng, Li-Hua, Jiang, Zhi-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076819/
https://www.ncbi.nlm.nih.gov/pubmed/32020873
http://dx.doi.org/10.1186/s12906-020-2831-y