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Synthesis of crocetin derivatives and their potent inhibition in multiple tumor cells proliferation and inflammatory property of macrophage
BACKGROUND: Crocetin is a major active component of saffron, which has a wide range of pharmacological effects. However, due to its low solubility, the pharmacological effects of crocetin cannot be better utilized. METHODS: In this study, we modified the chemical structure of crocetin by conjugating...
Autores principales: | Wang, Mao-Ze, Gao, Jin, Chu, Yang, Niu, Jie, Chen, Ming, Shang, Qiang, Peng, Li-Hua, Jiang, Zhi-Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076819/ https://www.ncbi.nlm.nih.gov/pubmed/32020873 http://dx.doi.org/10.1186/s12906-020-2831-y |
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