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DNA looping by two 5-methylcytosine-binding proteins quantified using nanofluidic devices

BACKGROUND: MeCP2 and MBD2 are members of a family of proteins that possess a domain that selectively binds 5-methylcytosine in a CpG context. Members of the family interact with other proteins to modulate DNA packing. Stretching of DNA–protein complexes in nanofluidic channels with a cross-section...

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Detalles Bibliográficos
Autores principales: Liu, Ming, Movahed, Saeid, Dangi, Saroj, Pan, Hai, Kaur, Parminder, Bilinovich, Stephanie M., Faison, Edgar M., Leighton, Gage O., Wang, Hong, Williams, David C., Riehn, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076939/
https://www.ncbi.nlm.nih.gov/pubmed/32178718
http://dx.doi.org/10.1186/s13072-020-00339-7