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Indirubin, a small molecular deriving from connectivity map (CMAP) screening, ameliorates obesity-induced metabolic dysfunction by enhancing brown adipose thermogenesis and white adipose browning

BACKGROUND: Obesity occurs when the body’s energy intake is constantly greater than its energy consumption and the pharmacological enhancing the activity of brown adipose tissue (BAT) and (or) browning of white adipose tissue (WAT) has been considered promising strategies to treat obesity. METHODS:...

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Detalles Bibliográficos
Autores principales: Wei, Gang, Sun, Honglin, Liu, Jun-li, Dong, Kai, Liu, Junli, Zhang, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076951/
https://www.ncbi.nlm.nih.gov/pubmed/32190098
http://dx.doi.org/10.1186/s12986-020-00440-4