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The conserved DNMT1-dependent methylation regions in human cells are vulnerable to neurotoxicant rotenone exposure

BACKGROUND: Allele-specific DNA methylation (ASM) describes genomic loci that maintain CpG methylation at only one inherited allele rather than having coordinated methylation across both alleles. The most prominent of these regions are germline ASMs (gASMs) that control the expression of imprinted g...

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Detalles Bibliográficos
Autores principales: Freeman, Dana M., Lou, Dan, Li, Yanqiang, Martos, Suzanne N., Wang, Zhibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076959/
https://www.ncbi.nlm.nih.gov/pubmed/32178731
http://dx.doi.org/10.1186/s13072-020-00338-8